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Connecting the Kinetics and Energy Landscape of tRNA Translocation on the Ribosome

Functional rearrangements in biomolecular assemblies result from diffusion across an underlying energy landscape. While bulk kinetic measurements rely on discrete state-like approximations to the energy landscape, single-molecule methods can project the free energy onto specific coordinates. With me...

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Detalles Bibliográficos
Main Authors: Whitford, Paul C., Blanchard, Scott C., Cate, Jamie H. D., Sanbonmatsu, Karissa Y.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605090/
https://ncbi.nlm.nih.gov/pubmed/23555233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003003
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