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Increased renal vasodilator prostanoids prevent hypertension in mice lacking the angiotensin subtype-2 receptor

The angiotensin subtype-1 (AT(1)) receptor mediates renal prostaglandin E(2) (PGE(2)) production, and pharmacological blockade of the angiotensin subtype-2 (AT(2)) receptor potentiates the action of angiotensin II (Ang II) to increase PGE(2) levels. We investigated the role of the AT(2) receptor in...

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Autors principals: Siragy, Helmy M., Senbonmatsu, Takaaki, Ichiki, Toshihiro, Inagami, Tadashi, Carey, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC408474/
https://ncbi.nlm.nih.gov/pubmed/10411547
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