Increased renal vasodilator prostanoids prevent hypertension in mice lacking the angiotensin subtype-2 receptor

The angiotensin subtype-1 (AT(1)) receptor mediates renal prostaglandin E(2) (PGE(2)) production, and pharmacological blockade of the angiotensin subtype-2 (AT(2)) receptor potentiates the action of angiotensin II (Ang II) to increase PGE(2) levels. We investigated the role of the AT(2) receptor in...

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Publicado en:	J Clin Invest
Autores principales:	Siragy, Helmy M., Senbonmatsu, Takaaki, Ichiki, Toshihiro, Inagami, Tadashi, Carey, Robert M.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1999
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411547/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI6063
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