Basolateral Na(+)/HCO(3)(–) cotransport activity is regulated by the dissociable Na(+)/H(+) exchanger regulatory factor

In the renal proximal tubule, the activities of the basolateral Na(+)/HCO(3)(–) cotransporter (NBC) and the apical Na(+)/H(+) exchanger (NHE3) uniformly vary in parallel, suggesting that they are coordinately regulated. PKA-mediated inhibition of NHE3 is mediated by a PDZ motif–containing protein, t...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Bernardo, Angelito A., Kear, Felicidad T., Santos, Anna V.P., Ma, Jianfei, Steplock, Debra, Robey, R. Brooks, Weinman, Edward J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1999
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5344
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