Basolateral Na(+)/HCO(3)(–) cotransport activity is regulated by the dissociable Na(+)/H(+) exchanger regulatory factor

In the renal proximal tubule, the activities of the basolateral Na(+)/HCO(3)(–) cotransporter (NBC) and the apical Na(+)/H(+) exchanger (NHE3) uniformly vary in parallel, suggesting that they are coordinately regulated. PKA-mediated inhibition of NHE3 is mediated by a PDZ motif–containing protein, t...

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Hauptverfasser: Bernardo, Angelito A., Kear, Felicidad T., Santos, Anna V.P., Ma, Jianfei, Steplock, Debra, Robey, R. Brooks, Weinman, Edward J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1999
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC408472/
https://ncbi.nlm.nih.gov/pubmed/10411549
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