Basolateral Na(+)/HCO(3)(–) cotransport activity is regulated by the dissociable Na(+)/H(+) exchanger regulatory factor

In the renal proximal tubule, the activities of the basolateral Na(+)/HCO(3)(–) cotransporter (NBC) and the apical Na(+)/H(+) exchanger (NHE3) uniformly vary in parallel, suggesting that they are coordinately regulated. PKA-mediated inhibition of NHE3 is mediated by a PDZ motif–containing protein, t...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Bernardo, Angelito A., Kear, Felicidad T., Santos, Anna V.P., Ma, Jianfei, Steplock, Debra, Robey, R. Brooks, Weinman, Edward J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1999
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5344
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