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Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development

Prostaglandin G and H synthases, or cyclooxygenases (COXs), catalyze the formation of prostaglandins (PGs). Whereas COX-1 is diffusely expressed in lymphoid cells in embryonic day 15.5 thymus, COX-2 expression is sparse, apparently limited to stromal cells. By contrast, COX-2 is predominant in a sub...

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Detalhes bibliográficos
Main Authors: Rocca, Bianca, Spain, Lisa M., Puré, Ellen, Langenbach, Robert, Patrono, Carlo, FitzGerald, Garret A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408457/
https://ncbi.nlm.nih.gov/pubmed/10330429
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