Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia

We recently identified a new gene, klotho, which is involved in the suppression of multiple aging phenotypes. The mouse homozygous for a disruption of the klotho locus (kl/kl) exhibited multiple pathological conditions resembling human aging. Histomorphometric analysis revealed low-turnover osteopen...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Kawaguchi, Hiroshi, Manabe, Noriyo, Miyaura, Chisato, Chikuda, Hirotaka, Nakamura, Kozo, Kuro-o, Makoto
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1999
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10430604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5705
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!