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Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia

We recently identified a new gene, klotho, which is involved in the suppression of multiple aging phenotypes. The mouse homozygous for a disruption of the klotho locus (kl/kl) exhibited multiple pathological conditions resembling human aging. Histomorphometric analysis revealed low-turnover osteopen...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kawaguchi, Hiroshi, Manabe, Noriyo, Miyaura, Chisato, Chikuda, Hirotaka, Nakamura, Kozo, Kuro-o, Makoto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC408412/
https://ncbi.nlm.nih.gov/pubmed/10430604
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