Oligospermic infertility associated with an androgen receptor mutation that disrupts interdomain and coactivator (TIF2) interactions

Structural changes in the androgen receptor (AR) are one of the causes of defective spermatogenesis. We screened the AR gene of 173 infertile men with impaired spermatogenesis and identified 3 of them, unrelated, who each had a single adenine→guanine transition that changed codon 886 in exon 8 from...

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發表在:	J Clin Invest
Principais autores:	Ghadessy, Farid J., Lim, Joyce, Abdullah, Abdullah A.R., Panet-Raymond, Valerie, Choo, Chee Keong, Lumbroso, Rose, Tut, Thein G., Gottlieb, Bruce, Pinsky, Leonard, Trifiro, Mark A., Yong, Eu Leong
格式:	Artigo
語言:	Inglês
出版:	American Society for Clinical Investigation 1999
主題:	Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408364/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4289
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