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Oligospermic infertility associated with an androgen receptor mutation that disrupts interdomain and coactivator (TIF2) interactions

Structural changes in the androgen receptor (AR) are one of the causes of defective spermatogenesis. We screened the AR gene of 173 infertile men with impaired spermatogenesis and identified 3 of them, unrelated, who each had a single adenine→guanine transition that changed codon 886 in exon 8 from...

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Bibliografski detalji
Glavni autori: Ghadessy, Farid J., Lim, Joyce, Abdullah, Abdullah A.R., Panet-Raymond, Valerie, Choo, Chee Keong, Lumbroso, Rose, Tut, Thein G., Gottlieb, Bruce, Pinsky, Leonard, Trifiro, Mark A., Yong, Eu Leong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC408364/
https://ncbi.nlm.nih.gov/pubmed/10359561
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