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Complement-mediated injury and protection of endothelium: Lessons from atypical haemolytic uraemic syndrome
The complement system provides a vital defence against invading pathogens. As an intrinsic system it is always ‘on’, in a state of constant, low level activation. This activation is principally mediated through the deposition of C3b on to pathogenic surfaces and host tissues. C3b is generated by spo...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083254/ https://ncbi.nlm.nih.gov/pubmed/21855165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2011.07.028 |
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