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Complement-mediated injury and protection of endothelium: Lessons from atypical haemolytic uraemic syndrome

The complement system provides a vital defence against invading pathogens. As an intrinsic system it is always ‘on’, in a state of constant, low level activation. This activation is principally mediated through the deposition of C3b on to pathogenic surfaces and host tissues. C3b is generated by spo...

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Sonraí Bibleagrafaíochta
Main Authors: Kerr, Heather, Richards, Anna
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083254/
https://ncbi.nlm.nih.gov/pubmed/21855165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2011.07.028
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