A high-throughput screen to identify inhibitors of SOD1 transcription

Amyotrophic lateral sclerosis (ALS) is a fatal degenerative motor neuron disease. Approximately 20% of familial ALS cases are caused by mutations in the Cu/Zn superoxide dismutase (SOD1) gene. Rodents expressing mutant SOD1 transgenes develop progressive, fatal motor neuron disease and disease onset...

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Hlavní autoři: Wright, Paul D, Wightman, Nicholas, Huang, Mickey, Weiss, Alexandra, Sapp, Peter C, Cuny, Gregory D, Ivinson, Adrian J, Glicksman, Marcie A, Ferrante, Robert J, Matson, Wayne, Matson, Samantha, Brown, Robert H
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083181/
https://ncbi.nlm.nih.gov/pubmed/22652679
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