טוען...

Screening for inhibitors of the SOD1 gene promoter: pyrimethamine does not reduce SOD1 levels in cell and animal models

Mutations in the Cu/Zn superoxide dismutase (SOD1) gene are detected in 20% of familial and 3% of sporadic amyotrophic lateral sclerosis (ALS) cases. Although mutant SOD1 is known to induce motor neuron death via multiple adverse acquired functions, its exact pathogenic mechanism is not well defined...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Wright, Paul D, Huang, Mickey, Weiss, Alexandra, Matthews, Jonathan, Wightman, Nicholas, Glicksman, Marcie, Brown, Robert H
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962987/
https://ncbi.nlm.nih.gov/pubmed/20638444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.07.020
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!