Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV‐134

Pancreatic adenocarcinoma is highly resistant to conventional therapeutics and has been shown to evade apoptosis by deregulation of the X‐linked and cellular inhibitors of apoptosis proteins (XIAP and cIAP). Second mitochondria‐derived activator of caspases (Smac) induces and amplifies cell death by...

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Detalhes bibliográficos
Main Authors: Hashim, Yassar M., Spitzer, Dirk, Vangveravong, Suwanna, Hornick, Mary C., Garg, Gunjal, Hornick, John R., Goedegebuure, Peter, Mach, Robert H., Hawkins, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082741/
https://ncbi.nlm.nih.gov/pubmed/24731702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.03.005
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