Lataa...
Differential Effects of Ethanol on Spectral Binding and Inhibition of Cytochrome P450 3A4 with Eight Protease Inhibitors Antiretroviral Drugs
BACKGROUND: Cytochrome P450 3A4 (CYP3A4) is the most abundant CYP enzyme in the liver, which metabolizes approximately 50% of the marketed drugs including antiretroviral agents. CYP3A4 induction by ethanol and its impact on drug metabolism and toxicity is known. However, CYP3A4–ethanol physical inte...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4082664/ https://ncbi.nlm.nih.gov/pubmed/21682753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01575.x |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|