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The effect of ethanol on drug oxidations in vitro and the significance of ethanol–cytochrome P-450 interaction

The effect of ethanol on N-demethylation of aminopyrine in rat liver slices and in the microsomal fraction and on microsomal hydroxylation of pentobarbital and aniline was studied. With liver slices N-demethylation of aminopyrine was stimulated by 35–40% at low ethanol concentrations (2mm), whereas...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Cinti, Dominick L., Grundin, Robert, Orrenius, Sten
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1973
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177821/
https://ncbi.nlm.nih.gov/pubmed/16742795
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