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Cytochrome P450 3A and P-glycoprotein drug–drug interactions with voclosporin
AIMS: Voclosporin is a novel calcineurin inhibitor intended for prevention of organ graft rejection and treatment of lupus nephritis. Pharmacokinetic drug interactions between voclosporin and a CYP3A inhibitor, inducer and substrate and a P-glycoprotein inhibitor and substrate were evaluated. METHOD...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4093929/ https://ncbi.nlm.nih.gov/pubmed/24330024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12309 |
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