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Surfactant protein-A enhances respiratory syncytial virus clearance in vivo

To determine the role of surfactant protein-A(SP-A) in antiviral host defense, mice lacking SP-A (SP-A(–/–)) were produced by targeted gene inactivation. SP-A(–/–) and control mice (SP-A(+/+)) were infected with respiratory syncytial virus (RSV) by intratracheal instillation. Pulmonary infiltration...

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Detalhes bibliográficos
Principais autores: LeVine, Ann Marie, Gwozdz, Jodie, Stark, James, Bruno, Michael, Whitsett, Jeffrey, Korfhagen, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408263/
https://ncbi.nlm.nih.gov/pubmed/10194474
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