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Heteropolymerization of S, I, and Z α(1)-antitrypsin and liver cirrhosis

The association between Z α(1)-antitrypsin deficiency and juvenile cirrhosis is well-recognized, and there is now convincing evidence that the hepatic inclusions are the result of entangled polymers of mutant Z α(1)-antitrypsin. Four percent of the northern European Caucasian population are heterozy...

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Publicado no:J Clin Invest
Principais autores: Mahadeva, Ravi, Chang, Wun-Shaing W., Dafforn, Timothy R., Oakley, Diana J., Foreman, Richard C., Calvin, Jacqueline, Wight, Derek G.D., Lomas, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10194472/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4874
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