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Amyloid fibrils nucleated and organized by DNA origami constructions

Amyloid fibrils are ordered, insoluble protein aggregates that are associated with neurodegenerative conditions such as Alzheimer’s disease(1). The fibrils have a common rod-like core structure, formed from an elongated stack of β-strands, and have a rigidity similar to silk (Young’s modulus of 0.2-...

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Hlavní autoři: Udomprasert, Anuttara, Bongiovanni, Marie N., Sha, Ruojie, Sherman, William B., Wang, Tong, Arora, Paramjit S., Canary, James W., Gras, Sally L., Seeman, Nadrian C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082467/
https://ncbi.nlm.nih.gov/pubmed/24880222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2014.102
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