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Withdrawal from chronic exposure to amphetamine, but not nicotine, leads to an immediate and enduring deficit in motivated behavior without affecting social interaction in rats

Psychostimulant withdrawal leads to depressive symptoms, such as anhedonia and social dysfunction. We determined the effects of withdrawal from chronic exposure to nicotine (9 mg/kg/day salt, 28 days) or amphetamine (10 mg/kg/day salt, 7 days) on the motivated response for a sucrose reward and on so...

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Bibliografiske detaljer
Main Authors: Der-Avakian, Andre, Markou, Athina
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082429/
https://ncbi.nlm.nih.gov/pubmed/20571366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e32833c7cc8
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