Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation

Eitemau Tebyg

• Chemotherapy and terminal skeletal muscle differentiation in WT1‐mutant Wilms tumors
  gan: Royer‐Pokora, Brigitte, et al.
  Cyhoeddwyd: (2018)
• Comprehensive Biology and Genetics Compendium of Wilms Tumor Cell Lines with Different WT1 Mutations
  gan: Royer-Pokora, Brigitte, et al.
  Cyhoeddwyd: (2020)
• Different CTNNB1 mutations as molecular genetic proof for the independent origin of four Wilms tumours in a patient with a novel germ line WT1 mutation
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  Cyhoeddwyd: (2007)
• Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15
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  Cyhoeddwyd: (2016)
• Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal–predominant histology
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  Cyhoeddwyd: (1997)