Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15

We describe a stromal predominant Wilms tumor with focal anaplasia and a complex, tumor specific chromosome 11 aberration: a homozygous deletion of the entire WT1 gene within a heterozygous 11p13 deletion and an additional region of uniparental disomy (UPD) limited to 11p15.5-p15.2 including the IGF...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brandt, Artur, Löhers, Katharina, Beier, Manfred, Leube, Barbara, de Torres, Carmen, Mora, Jaume, Arora, Parineeta, Jat, Parmjit S., Royer-Pokora, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876997/
https://ncbi.nlm.nih.gov/pubmed/27213811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155561
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