Deletion of WT1 and WIT1 Genes and Loss of Heterozygosity on Chromosome 11p in Wilms Tumors in Japan

Six of 39 sporadic Wilms tumors had gross homozygous or hemizygous WT1 and WIT1 deletions. Two Wilms tumor‐aniridia‐genitourinary abnormalities‐mental retardation syndrome patients had total hemizygous WT1 and WIT1 deletions in both constitutional and nonsporadic type tumor cells. Four of the 8 tumo...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Kaneko, Yasuhiko, Takeda, Osamu, Homma, Chieko, Maseki, Nobuo, Miyoshi, Hiroyuki, Tsunematsu, Yukiko, Williams, Bryan G., Saunders, Grady F., Sakurai, Masaharu
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1993
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919323/
https://ncbi.nlm.nih.gov/pubmed/8393432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb02021.x
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