Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT.

The inactivation of two alleles at a locus on the short arm of chromosome 11 (band 11p13) has been suggested to be critical steps in the development of Wilms tumor (WT), a childhood kidney tumor. Two similar candidate WT cDNA clones (WT33 and LK15) have recently been identified on the basis of both...

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Main Authors: Huff, V, Miwa, H, Haber, D A, Call, K M, Housman, D, Strong, L C, Saunders, G F
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683037/
https://ncbi.nlm.nih.gov/pubmed/1673293
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