Ca(2+) Influx via the Na(+)/Ca(2+) Exchanger Is Enhanced in Malignant Hyperthermia Skeletal Muscle

Malignant hyperthermia (MH) is potentially fatal pharmacogenetic disorder of skeletal muscle caused by intracellular Ca(2+) dysregulation. NCX is a bidirectional transporter that effluxes (forward mode) or influxes (reverse mode) Ca(2+) depending on cellular activity. Resting intracellular calcium (...

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Autores principales: Altamirano, Francisco, Eltit, José M., Robin, Gaëlle, Linares, Nancy, Ding, Xudong, Pessah, Isaac N., Allen, Paul D., López, José R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081953/
https://ncbi.nlm.nih.gov/pubmed/24847052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550764
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