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Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca(2+) channel and the type 1 ryanodine receptor
Malignant hyperthermia (MH) susceptibility is a dominantly inherited disorder in which volatile anesthetics trigger aberrant Ca(2+) release in skeletal muscle and a potentially fatal rise in perioperative body temperature. Mutations causing MH susceptibility have been identified in two proteins crit...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356662/ https://ncbi.nlm.nih.gov/pubmed/22547813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119207109 |
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