Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca(2+) channel and the type 1 ryanodine receptor

Malignant hyperthermia (MH) susceptibility is a dominantly inherited disorder in which volatile anesthetics trigger aberrant Ca(2+) release in skeletal muscle and a potentially fatal rise in perioperative body temperature. Mutations causing MH susceptibility have been identified in two proteins crit...

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Detalhes bibliográficos
Main Authors: Eltit, Jose Miguel, Bannister, Roger A., Moua, Ong, Altamirano, Francisco, Hopkins, Philip M., Pessah, Isaac N., Molinski, Tadeusz F., López, Jose R., Beam, Kurt G., Allen, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356662/
https://ncbi.nlm.nih.gov/pubmed/22547813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119207109
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