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Defective regulation of the epithelial Na(+) channel by Nedd4 in Liddle's syndrome
Liddle's syndrome is an inherited form of hypertension linked to mutations in the epithelial Na(+) channel (ENaC). ENaC is composed of three subunits (α, β, γ), each containing a COOH-terminal PY motif (xPPxY). Mutations causing Liddle's syndrome alter or delete the PY motifs of β- or γ-EN...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC408130/ https://ncbi.nlm.nih.gov/pubmed/10074483 |
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