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Lessons from miR-143/145: the importance of cell-type localization of miRNAs

miR-143 and miR-145 are co-expressed microRNAs (miRNAs) that have been extensively studied as potential tumor suppressors. These miRNAs are highly expressed in the colon and are consistently reported as being downregulated in colorectal and other cancers. Through regulation of multiple targets, they...

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Bibliographic Details
Main Authors: Kent, Oliver A., McCall, Matthew N., Cornish, Toby C., Halushka, Marc K.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081080/
https://ncbi.nlm.nih.gov/pubmed/24875473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku461
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