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RREB1 repressed miR-143/145 modulates KRAS signaling through downregulation of multiple targets
A lack of expression of miR-143 and miR-145 has been demonstrated to be a frequent feature of colorectal tumors. Activating KRAS mutations have been reported in 30–60% of colorectal cancers and an inverse correlation between Kras and miR-143/145 expression has been observed. Previously, we have demo...
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| Опубликовано в: : | Oncogene |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8177721/ https://ncbi.nlm.nih.gov/pubmed/22751122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.266 |
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