SPIB and BATF provide alternate determinants of IRF4 occupancy in diffuse large B-cell lymphoma linked to disease heterogeneity

Interferon regulatory factor 4 (IRF4) is central to the transcriptional network of activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL), an aggressive lymphoma subgroup defined by gene expression profiling. Since cofactor association modifies transcriptional regulatory input by IRF4, we a...

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Detalhes bibliográficos
Main Authors: Care, Matthew A., Cocco, Mario, Laye, Jon P., Barnes, Nicholas, Huang, Yuanxue, Wang, Ming, Barrans, Sharon, Du, Ming, Jack, Andrew, Westhead, David R., Doody, Gina M., Tooze, Reuben M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081075/
https://ncbi.nlm.nih.gov/pubmed/24875472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku451
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