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Force-induced melting of DNA—evidence for peeling and internal melting from force spectra on short synthetic duplex sequences
Overstretching of DNA occurs at about 60–70 pN when a torsionally unconstrained double-stranded DNA molecule is stretched by its ends. During the transition, the contour length increases by up to 70% without complete strand dissociation. Three mechanisms are thought to be involved: force-induced mel...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081069/ https://ncbi.nlm.nih.gov/pubmed/24838568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku441 |
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