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Single-Molecule Atomic Force Spectroscopy Reveals that DnaD Forms Scaffolds and Enhances Duplex Melting

The Bacillus subtilis DnaD is an essential DNA-binding protein implicated in replication and DNA remodeling. Using single-molecule atomic force spectroscopy, we have studied the interaction of DnaD and its domains with DNA. Our data reveal that binding of DnaD to immobilized single molecules of dupl...

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Bibliografiske detaljer
Main Authors: Zhang, Wenke, Machón, Cristina, Orta, Alberto, Phillips, Nicola, Roberts, Clive J., Allen, Stephanie, Soultanas, Panos
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033579/
https://ncbi.nlm.nih.gov/pubmed/18291414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.067
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