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PolyUbiquitin Chain Linkage Topology Selects the Functions from the Underlying Binding Landscape

Ubiquitin (Ub) can generate versatile molecular signals and lead to different celluar fates. The functional poly-valence of Ub is believed to be resulted from its ability to form distinct polymerized chains with eight linkage types. To provide a full picture of ubiquitin code, we explore the binding...

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Hlavní autoři: Wang, Yong, Tang, Chun, Wang, Erkang, Wang, Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081019/
https://ncbi.nlm.nih.gov/pubmed/24992446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003691
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