CAR-dependent and CAR-independent pathways of adenovirus vector–mediated gene transfer and expression in human fibroblasts

Primary fibroblasts are not efficiently transduced by subgroup C adenovirus (Ad) vectors because they express low levels of the high-affinity Coxsackie virus and adenovirus receptor (CAR). In the present study, we have used primary human dermal fibroblasts as a model to explore strategies by which A...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Hidaka, Chisa, Milano, Eric, Leopold, Philip L., Bergelson, Jeffrey M., Hackett, Neil R., Finberg, Robert W., Wickham, Thomas J., Kovesdi, Imre, Roelvink, Peter, Crystal, Ronald G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1999
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10021467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5309
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