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CAR-dependent and CAR-independent pathways of adenovirus vector–mediated gene transfer and expression in human fibroblasts

Primary fibroblasts are not efficiently transduced by subgroup C adenovirus (Ad) vectors because they express low levels of the high-affinity Coxsackie virus and adenovirus receptor (CAR). In the present study, we have used primary human dermal fibroblasts as a model to explore strategies by which A...

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Detalhes bibliográficos
Main Authors: Hidaka, Chisa, Milano, Eric, Leopold, Philip L., Bergelson, Jeffrey M., Hackett, Neil R., Finberg, Robert W., Wickham, Thomas J., Kovesdi, Imre, Roelvink, Peter, Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408101/
https://ncbi.nlm.nih.gov/pubmed/10021467
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