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GM-CSF–deficient mice are susceptible to pulmonary group B streptococcal infection

Granulocyte-macrophage colony-stimulating factor (GM-CSF) gene-targeted mice (GM(–/–)) cleared group B streptococcus (GBS) from the lungs more slowly than wild-type mice. Expression of GM-CSF in the respiratory epithelium of GM(–/–) mice improved bacterial clearance to levels greater than that in wi...

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Détails bibliographiques
Auteurs principaux: LeVine, Ann Marie, Reed, Jacquelyn A., Kurak, Kim E., Cianciolo, Eli, Whitsett, Jeffrey A.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC408099/
https://ncbi.nlm.nih.gov/pubmed/10021465
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