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GM-CSF–deficient mice are susceptible to pulmonary group B streptococcal infection

Granulocyte-macrophage colony-stimulating factor (GM-CSF) gene-targeted mice (GM(–/–)) cleared group B streptococcus (GBS) from the lungs more slowly than wild-type mice. Expression of GM-CSF in the respiratory epithelium of GM(–/–) mice improved bacterial clearance to levels greater than that in wi...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: LeVine, Ann Marie, Reed, Jacquelyn A., Kurak, Kim E., Cianciolo, Eli, Whitsett, Jeffrey A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408099/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10021465/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5212
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