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Stable activity of diabetogenic cells with age in NOD mice: dynamics of reconstitution and adoptive diabetes transfer in immunocompromised mice

The non-obese diabetic (NOD) mouse is a prevalent disease model of type 1 diabetes. Immune aberrations that cause and propagate autoimmune insulitis in these mice are being continually debated, with evidence supporting both dominance of effector cells and insufficiency of suppressor mechanisms. In t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kaminitz, Ayelet, Mizrahi, Keren, Ash, Shifra, Ben-Nun, Avi, Askenasy, Nadir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080962/
https://ncbi.nlm.nih.gov/pubmed/24601987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12277
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