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Stable activity of diabetogenic cells with age in NOD mice: dynamics of reconstitution and adoptive diabetes transfer in immunocompromised mice

The non-obese diabetic (NOD) mouse is a prevalent disease model of type 1 diabetes. Immune aberrations that cause and propagate autoimmune insulitis in these mice are being continually debated, with evidence supporting both dominance of effector cells and insufficiency of suppressor mechanisms. In t...

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Detalhes bibliográficos
Main Authors: Kaminitz, Ayelet, Mizrahi, Keren, Ash, Shifra, Ben-Nun, Avi, Askenasy, Nadir
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080962/
https://ncbi.nlm.nih.gov/pubmed/24601987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12277
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