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Prolonged antibiotic treatment induces a diabetogenic intestinal microbiome that accelerates diabetes in NOD mice

Accumulating evidence supports that the intestinal microbiome is involved in Type 1 diabetes (T1D) pathogenesis through the gut-pancreas nexus. Our aim was to determine whether the intestinal microbiota in the non-obese diabetic (NOD) mouse model played a role in T1D through the gut. To examine the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ISME J
Hauptverfasser: Brown, Kirsty, Godovannyi, Artem, Ma, Caixia, Zhang, YiQun, Ahmadi-Vand, Zahra, Dai, Chaunbin, Gorzelak, Monika A, Chan, YeeKwan, Chan, Justin M, Lochner, Arion, Dutz, Jan P, Vallance, Bruce A, Gibson, Deanna L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737925/
https://ncbi.nlm.nih.gov/pubmed/26274050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ismej.2015.114
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