Inhibitors of collagenase but not of gelatinase reduce cartilage explant proteoglycan breakdown despite only low levels of matrix metalloproteinase activity

Aims—To investigate the level of matrix metalloproteinase activity during the time-course of cartilage explant proteoglycan breakdown; to determine the effects of selective small-molecule inhibitors of matrix metalloproteinases on proteoglycan degradation. Methods—The levels of matrix metalloprotein...

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Detalhes bibliográficos

Publicado no:	Clin Mol Pathol
Principais autores:	Brown, Carol J, Rahman, Shamim, Morton, Allison C, Beauchamp, Claire L, Bramwell, Helena, Buttle, David J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMJ Publishing Group 1996
Assuntos:	Papers
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16696099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/mp.49.6.m331
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