Inhibitors of collagenase but not of gelatinase reduce cartilage explant proteoglycan breakdown despite only low levels of matrix metalloproteinase activity

Aims—To investigate the level of matrix metalloproteinase activity during the time-course of cartilage explant proteoglycan breakdown; to determine the effects of selective small-molecule inhibitors of matrix metalloproteinases on proteoglycan degradation. Methods—The levels of matrix metalloprotein...

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Detalles Bibliográficos

Publicado en:	Clin Mol Pathol
Autores principales:	Brown, Carol J, Rahman, Shamim, Morton, Allison C, Beauchamp, Claire L, Bramwell, Helena, Buttle, David J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMJ Publishing Group 1996
Materias:	Papers
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16696099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/mp.49.6.m331
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