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Orally Available Small-Molecule Polymerase Inhibitor Cures a Lethal Morbillivirus Infection

Measles virus (MeV) is a highly infectious morbillivirus responsible for major human morbidity and mortality in the non-vaccinated. The related, zoonotic canine distemper virus (CDV) induces morbillivirus disease in ferrets with 100% lethality. We report an orally available, shelf-stable pan-morbill...

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書誌詳細
主要な著者: Krumm, Stefanie A, Yan, Dan, Hovingh, Elise S, Evers, Taylor J, Enkirch, Theresa, Reddy, G. Prabhakar, Sun, Aiming, Saindane, Manohar T, Arrendale, Richard F, Painter, George, Liotta, Dennis C, Natchus, Michael G, von Messling, Veronika, Plemper, Richard K
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080709/
https://ncbi.nlm.nih.gov/pubmed/24739760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008517
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