Non-nucleoside Inhibitors of the Measles Virus RNA-dependent RNA Polymerase: Synthesis, Structure-Activity Relationships and Pharmacokinetics

The measles virus (MeV), a member of the paramyxovirus family, is an important cause of pediatric morbidity and mortality worldwide. In an effort to provide therapeutic treatments for improved measles management, we previously identified a small, non-nucleoside organic inhibitor of the viral RNA-dep...

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Detalhes bibliográficos
Main Authors: Ndungu, J. Maina, Krumm, Stefanie A., Yan, Dan, Arrendale, Richard F., Reddy, G. Prabhakar, Evers, Taylor, Howard, Randy, Natchus, Michael G., Saindane, Manohar T., Liotta, Dennis C., Plemper, Richard K., Snyder, James P., Sun, Aiming
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701436/
https://ncbi.nlm.nih.gov/pubmed/22480182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201699w
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