Promoter hypomethylation of EpCAM-regulated bone morphogenetic protein gene family in recurrent endometrial cancer

PURPOSE: Epigenetic regulation by promoter methylation plays a key role in tumorigenesis. Our goal was to investigate whether altered DNA methylation signatures associated with oncogenic signaling delineate biomarkers predictive of endometrial cancer recurrence. EXPERIMENTAL DESIGN: Methyl-CpG-captu...

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Autori principali: Hsu, Ya-Ting, Gu, Fei, Huang, Yi-Wen, Liu, Joseph, Ruan, Jianhua, Huang, Rui-Lan, Wang, Chiou-Miin, Chen, Chun-Liang, Lai, Hung-Cheng, Mutch, David G., Goodfellow, Paul J., Thompson, Ian M., Kirma, Nameer B., Huang, Tim Hui-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080631/
https://ncbi.nlm.nih.gov/pubmed/24077349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1734
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