Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception

Cell surface reception of Sonic hedgehog (Shh) must ensure that the graded morphogenic signal is interpreted accordingly in neighboring cells to specify tissue patterns during development. Here, we report endocytic sorting signals for the receptor Patched1 (Ptch1), comprising two ‘PPXY’ motifs, that...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yue, Shen, Tang, Liu-Ya, Tang, Ying, Tang, Yi, Shen, Qiu-Hong, Ding, Jie, Chen, Yan, Zhang, Zengdi, Yu, Ting-Ting, Zhang, Ying E, Cheng, Steven Y
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2014
Pynciau:
Developmental Biology and Stem Cells
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080449/
https://ncbi.nlm.nih.gov/pubmed/24925320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02555
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