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An 11-nt sequence polymorphism at the 3′UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell culture

Surfactant protein A (SP-A) plays a vital role in maintaining normal lung function and in host defense. Two genes encode SP-A in humans (SFTPA1, SFTPA2), and several gene variants have been identified for these. We have previously shown that sequence elements of SFTPA1 and SFTPA2 3′ untranslated reg...

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Detaylı Bibliyografya
Asıl Yazarlar: Silveyra, Patricia, DiAngelo, Susan L., Floros, Joanna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080286/
https://ncbi.nlm.nih.gov/pubmed/24793167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00313.2013
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