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Human SP-A1 (SFTPA1) variant-specific 3′ UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene

Human surfactant protein A (SP-A) is encoded by two functional genes (SFTPA1, SFTPA2) with a high degree of sequence identity. Sequence differences among these genes and their genetic variants have been observed at the 5′ and 3′ untranslated regions (UTRs). In this work, we studied the impact on tra...

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Bibliografiska uppgifter
Huvudupphovsmän: Silveyra, Patricia, Wang, Guirong, Floros, Joanna
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957414/
https://ncbi.nlm.nih.gov/pubmed/20693318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00113.2010
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