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Human SP-A1 (SFTPA1) variant-specific 3′ UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene

Human surfactant protein A (SP-A) is encoded by two functional genes (SFTPA1, SFTPA2) with a high degree of sequence identity. Sequence differences among these genes and their genetic variants have been observed at the 5′ and 3′ untranslated regions (UTRs). In this work, we studied the impact on tra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Silveyra, Patricia, Wang, Guirong, Floros, Joanna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957414/
https://ncbi.nlm.nih.gov/pubmed/20693318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00113.2010
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